Who discovered that stress leads to three distinct stages of physiological change?
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The fight-or-flight response (also called the stress response) is a physiological reaction that occurs in response to a perceived threat or danger. This enables the body to take action quickly, and is intended to keep us out of (physical) harm’s way. Unfortunately for our health, this response also occurs when we are not in any immediate physical danger, but are still experiencing stress. For example, this can happen when someone is running late for an appointment or class, and is feeling stressed about trying to get there. Show
The physical changes that occur during this response can cause wear and tear within the body if the perception of stress persists. Here are a few examples of such bodily changes:
For additional information about how these physiological changes occur, click here to read more. The fight-or-flight response is also recognized as the first stage of the General Adaptation Syndrome. General Adaptation Syndrome Stages of the General Adaptation Syndrome Homeostasis is a state of physiological calmness or balance, and occurs when our bodily functions are running smoothly in conjunction with low stress levels. When exposed to stressors, this causes an imbalance to occur as the body responds to the perceived threat, and then tries to return to normal functioning. The general adaptation syndrome (GAS), developed by Hans Selye, describes the pattern of responses that the body goes through after being prompted by a stressor. There are three stages: alarm, resistance, and exhaustion.
These changes will occur in the body regardless of whether the perceived stressor is considered eustress (positive or pleasant) or distress (negative or unpleasant). Ultimately, this means that we need to take active steps in managing all of our stressors, as it can build up and potentially cause harm to our health otherwise. Throughout human evolution, our survival has been contingent on an ability to survive life-threatening situations — from being hunted by predators to recovering from illnesses. But how do we become consciously aware that a situation is dangerous so that we might adapt to (and survive) it? Often, we are first alerted that a situation is threatening by one of the side effects of stress — our heart rate increases, for example, and we become aware goosebumps on the skin, amongst other physical symptoms. A Vienna-born endocrinologist by name of Hans Selye (1907-1982) was the first scientist to single out these side effects and to identify them collectively as being the result of 'stress' — a term that we use routinely today, but which did not even exist until less than 100 years ago. Whilst conducting experiments relating to hormone production, Selye noticed that his subjects showed a similar set of side effects regardless of the type of life-threatening stimulus that researchers presented to them. Seyle termed this collection of responses general adaptation syndrome (GAS), a 3-stage set of physiological processes which prepare, or adapt, the body for danger so that we ready to stand a better chance of surviving it compared to if we remained passively relaxed when faced with a threat. Discovery of GASWho was Hans Selye?Hans Selye was born in Vienna, Austro-Hungary in 1907. He graduated with an MD from the German University of Prague in 1929, received a PhD in 1931 and the following year, accepted a position at McGill University in Montreal, Canada to continue his biochemistry research. Whilst at McGill, in a 1926 article in Nature entitled, “A Syndrome produced by Diverse Nocuous Agents”, he identified a set of symptoms of being exposed to various threats in rats as general adaptation syndrome, and later labelled “stress” as we understand it today. Selye died in Montreal in 1982 at the age of 75. General adaptation syndrome was discovered accidentally by Selye whilst he was conducting experiments on rats at McGill University in Montreal, Canada. In a 1926 letter to Nature, Selye described the findings of a series of experiments on rats, in which the animals were subjected to numerous stressors, which he referred to as “nocuous agents”, including exposure to cold temperatures, injection with various toxins and being forced to endure excessive physical exertion (Selye, 1926).1 He then observed the physiological responses to these stressful situations. Selye noted that regardless of the type of shock the rats were exposed to, a similar set of symptoms could be observed shortly afterwards, indicating that the reaction was not to a specific stimulus but part of a more general reaction to stressful situations. Selye went on to identify three distinct stages of general adaptation syndrome — the initial alarm reaction stage which occurs shortly after the stressful event, followed by a resistance stage, during which body's Autonomic Nervous System (ANS) resists the impact of the stressful stimulus, and finally, if the stress continues, the exhaustion stage, when the body fails to cope with the distressing stimulus. Stage 1: Alarm ReactionThe alarm reaction stage is the first sign of general adaptation syndrome and occurred in Selye's rats between 6 and 48 hours following the introduction of the “nocuous agent”. During this stage, the sympathetic branch of the ANS is activated — the adrenal gland secretes the stress hormone cortisol, along with adrenaline, and Selye observed that the rats' bodies underwent significant physical changes, including a reduction in bodily fat and the shrinking of numerous organs, including the liver and thymus and lymph glands. The body temperature was also lowered, conserving energy (Selye, 1926). The alarm reaction stage prepares animals for a fight-or-flight response — a term coined by Walter Cannon to describe our reaction to a stressful event. The body adapts to be able to react quickly in either fleeing or confronting the threat posed to them. RelatedStage 2: ResistanceAfter the initial reaction to the stressor during the alarm reaction stage, the parasympathetic branch of the ANS counteracts the changes that the stressful stimulus has produced, and attempts to restore a state of homeostasis, the default state in which the body functions normally. This stage, in which the body tries to adapt to the new situation, is referred to as the resistance stage. Selye found that it occurred in the rats typically 48 hours following the stressful event. During the resistance stage, the results of the hormonal changes which occurred in the previous stage are still apparent, including increased glucose levels in the blood and and higher blood pressure, but stress hormone levels begin to return to normal, enabling the body's focus to shift from alertness to repair. Stage 3: ExhaustionThe final phase of general adaptation syndrome is the exhaustion stage, in which the body has depleted resources following its attempt to repair itself during the preceding resistance stage. If the original threat has passed, it will continue its recovery. However, the body no longer has the energy to cope with continued stress in the long term, and should it continue, it begins to show signs of exhaustion, gradually deteriorating as it persists. A Short-Term Survival Strategy?The limited resources and energy that the body has to cope with stressful situations means that general adaptation syndrome has evolved to be only useful to animals' survival in the short term — that is, if the threat does not persist, leading to exhaustion. For example, a rush of adrenaline might enable prey to flee an approaching predator, but the persistent stress of being hunted continuously for days would be difficult to adapt to in the long term. Individual DifferencesSelye himself acknowledged that stress impacts each individual differently (Selye, 1950).2 What one person considers to be a severely stressful situation, another person may experience as only mildly distressing. The GAS may also be manipulated by training — on experiencing stress on a regular basis, our bodies adapt to cope with it. This ability to manipulation our stress response is particularly useful for endurance sports and affects how athletes train for strenuous competitions. For instance, a long-distance runner may undergo endurance training in order to adapt to, and cope with, the stress of longer periods of physical exertion (Kraemer and Ratamess, 2004).3 Who defined stress as the response of the body to any demand?The word 'stress' is used in physics to refer to the interaction between a force and the resistance to counter that force, and it was Hans Selye who first incorporated this term into the medical lexicon to describe the “nonspecific response of the body to any demand “.
Who among the following is a pioneer in stress research and coined the term general adaptation syndrome gas )?In 1936 Selye wrote about a stress condition known as general adaptation syndrome (GAS). He first observed the symptoms of GAS after injecting ovarian extracts into laboratory rats, an experiment he performed with the intent of discovering a new hormone.
What was the main point that Hans Selye emphasized about stress?In the mid-1930s Selye proposed that the human body adapted to a diverse range of stressors— including, extreme temperatures, intoxification, surgical trauma, physical exercise and complete immobilization—by releasing adrenocortical hormones to regulate bodily functions.
Which one of the following proposes that emotion is the result of interpretation of physiological change?The James-Lange theory of emotion postulates that emotions occur as a result of physical responses to events (physiological responses to stimuli directly cause subjective feelings).
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