How does verapamil affect heart rate?
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Community Stat Theor Method A8:191–205 Google Scholar Does verapamil cause fast heart rate?When used to treat arrhythmias, such as Atrial Fibrillation, verapamil prolongs the refractory period (the period immediately following electrical stimulation of the AV node) and slows the heart rate. Verapamil can also lower blood pressure.
How much does verapamil reduce heart rate?VO2, VCO2, and VE were also unaffected by verapamil administration. Heart rate during exercise was reduced dose-dependently (p less than 0.001). With the highest dose of verapamil, maximal heart rate was reduced by 13 +/- 1 beats X min-1.
Why does verapamil cause bradycardia?Both beta-adrenergic receptor antagonist drugs (beta-blockers) and non-dihydropyridine calcium-channel blockers (non-DHP CCBs), ie, diltiazem and verapamil, can cause sinus arrest or severe sinus bradycardia, and when drugs from the two classes are used together, these effects may be more than additive.
What should be monitored when taking verapamil?The clinician should monitor their blood pressure, heart rate, and liver function tests for patients who are on verapamil.
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